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KMID : 0032220190310040446
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Annals of Dermatology
2019 Volume.31 No. 4 p.446 ~ p.449
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Treatment of Hidradenitis Suppurativa Patient with Klinefelter Syndrome by Adalimumab
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Shin Ji-Yeoun
Hong Jung-Yeon
Lee Ho-Jung
Sim Chang-Yoon
Park Young-Lip
Lee Jong-Suk
Lee Sung-Yul
Kim Jung-Eun
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Abstract
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Hidradenitis suppurativa (HS) is a chronic, inflammatory and painful skin disease with recurrent nodules and tracts involving the intertriginous regions. It is known that the patient with HS shows an increased risk of metabolic disorders such as diabetes, metabolic syndrome and autoimmune diseases. Klinefelter syndrome (KS) is a sex chromosomal disorder occurring in males due to an abnormality of sexual differentiation, characterized by 47, XXY karyotype. Also, KS is related with somatic comorbidities such as metabolic syndrome, autoimmune and rheumatologic disorders as HS is. We report a HS patient with KS who shows a big improvement while on tumor necrosis factor-alpha inhibitor treatment.
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KEYWORD
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Hidradenitis suppurativa, Klinefelter syndrome
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